What is Ulcerative Colitis?
Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding.
Ulcerative colitis is closely related to another condition of inflammation of the intestines called Crohn's disease. Together, they are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn's diseases are chronic conditions that can last years to decades. They affect approximately 500,000 to 2 million people In the United States. Men and women are affected equally. They most commonly begin during adolescence and early adulthood, but they also can begin during childhood and later in life.
It is found worldwide, but is most common in the United States, England, and northern Europe. It is especially common in people of Jewish descent. Ulcerative colitis is rarely seen in Eastern Europe, Asia, and South America, and is rare in the black population. For unknown reasons, an increased frequency of this condition has been recently observed in developing nations.
First degree relatives of people with ulcerative colitis have an increased lifetime risk of developing the disease, but the overall risk remains small.
What Causes Ulcerative Colitis?
The causes of ulcerative colitis is not known. To date, there has been no convincing evidence that it is caused by infection or is contagious.
Ulcerative colitis likely involves abnormal activation of the immune system in the intestines. The immune system is composed of immune cells and the proteins that these cells produce. These cells and proteins serve to defend the body against harmful bacteria, viruses, fungi, and other foreign invaders. Activation of the immune system causes inflammation within the tissues where the activation occurs. (Inflammation is, in fact, an important mechanism of defense used by the immune system.) Normally, the immune system is activated only when the body is exposed to harmful invaders. In patients ulcerative colitis, however, the immune system is abnormally and chronically activated in the absence of any known invader. The continued abnormal activation of the immune systems causes chronic inflammation and ulceration. The susceptibility to abnormal activation of the immune system is genetically inherited. First degree relatives (brothers, sisters, children, and parents) of patients with IBD are thus more likely to develop these diseases.
In the last 1 to 2 years, there have been multiple studies using genome wide association scans investigating genetic susceptibility in ulcerative colitis. These studies have found there to be approximately 30 genes that might increase susceptibility to ulcerative colitis including immunoglobulin receptor gene FCGR2A, 5p15, 2p16, ORMDL3, ECM1, as well as regions on chromosomes 1p36, 12q15, 7q22, 22q13, and IL23R. At this early point in the research, it is still unclear how these genetic associations will be applied to treating the disease, but they might have future implications for understanding pathogenesis and creating new treatments.
First Steps
At integra Medical Center, our main concern is that you are convinced that our Stem Cell Therapy is the best option to treat your condition. That is why, before scheduling your appointment, we will need you to complete the following steps:- Fill-out the Patient History Form
- Read the documentation that we have on our website or the files we send to your e-mail.
- Send the Patient History Form back to us.
- Schedule your complimentary call with Dr. Gonzalez.
Talk to Dr. Gonzalez
We want you to get all your questions answered before deciding on receiving our Stem Cell Therapy. That's why we want you to be well documented and write down your questions before the call. Also, we recommend researching other providers and clinics so you know that your are going to get the best treatment at the most affordable price.At this time the doctor will let you know the exact cost of the therapy based on your condition and information you provided in the Patient History Form.
Scheduling your Appointment
Once you decide IMC's Stem Cell Therapy is the best treatment for your condition, your Patient Advocate will schedule a tentative date for your treatment. Appointment dates will become final when the initial deposit is received, which is usually 30% of the full treatment cost. The remaining balance can be transferred no later than 2 days before your appointment date.Travel Arrangements
Your Patient Advocate will be there to assist you with any questions you may have regarding air travel, lodging, ground transportation and even tourist attractions near the clinic. Usually, patients choose to stay in one of the Rio Grande Valley's major cities, such as McAllen, Weslaco or Donna.
Depending on the treatment package that you choose, your stay and ground transportation may be included with the cost of therapy, so all you have to worry about is air transportation. Be sure to ask your Patient Advocate what's included in your package.
IMC's Stem Cell Therapy Protocol
This method is the result of many years of experience. It has been very effective in making a powerful impact on the conditions we work on at Integra Medical Center. The steps of the protocol are as follows:The whole process takes about 2 hours to complete and after the final evaluation the patient is released and can return to their hotel. Some patients even return to their homes on that same day and back to work the very next day!
Stem cell treatments provided by Integra Medical Center occur in Mexico and hence are outside the boundaries of the U.S. and therefore are not currently approved by the FDA.
While the stem cell debate continues, Integra Medical Center is working towards documenting scientific proof so that we may be able to conduct treatments within the U.S., but at this point in time, our patients must come to us.
Be warned, stem cell treatments are not a cure for any condition, disease or injury. The information contained in this IMC's written materials should not be considered medical advice. It is intended to be used for educational and information purposes only.
